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Christina Applegate recorded the latest episode of her “MeSsy” podcast from a Los Angeles hospital bed where she revealed she’s been hospitalized with “so much pain” that she’s “screaming.”

On the Tuesday episode, the “Married… With Children” star told her listeners that she decided to go straight to the hospital while on a flight back from Europe, where she visited family.

“I’m staying here because I want answers. I want every test that you can possibly think of or ones that you haven’t even thought of, and I want them done,” she shared on the show, which she co-hosts with Jamie-Lynn Sigler.

Read more at https://pagesix.com/2025/08/05/celebrity-news/christina-applegate-hospitalized-suffering-from-so-much-pain-as-she-reveals-new-health-crisis/

#christinaapplegate #health

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19Comments

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  1. 1
    @mercywilliams2698

    What a shame to see these clips about your time with this chronic condition of MS. Hope you are able to find your way to some leveling out with the physical stress!

    I am nearing 69 with chronic never diagnosed immune system condition since childhood. Never having a firm fix on things is a long story. But the advantage is I learned the language and eventually the lay of the land with symptoms and mostly in my case an awareness I got sick at same time each year. Eventually omnipresent.

    Mine is a light disorder..the episodes follow the light shifts which include the equinoxes and solstices. I began taking Vitamin D in 2010 …following deficiency result at primary care. It is the only input I have had from primary care. The mood component I have to it was well managed beginning in 1992. But primary care never caught on to my physical distresses just thought seasonal meant psychological. So did I.

    The Vitamin D made things infinitely better for years. Then I picked up Covid and that lingered. In my case covid was a time of enlightenment. I realized I was likely experiencing my immune distress from a viral situation I had failed to move on from. Covid was like infectious mono years earlier..viral pneumonia bout ..childhood measles mumps. Everything left me with lingering malaise.

    If you are taking strong prescription medications for your MS…that can bring on an alternative narrative as your body may respond to the suppression of your immune system as a battle and collecting new symptoms may generate chaos. And then treatments to cope with that. And then more things to counter that. And pretty soon there is nothing but turmoil. I have been there!!!

    Some people with autoimmune conditions get relief from strong drugs. There are others like myself who benefit from a simpler less invasive approach. I keep a daily log listing meds and supplements with brief comments about sleep diet and activities.

    I treat myself round the clock. Trial and error I discovered I need Vitamin D all day and night to cope with light sensitivity. Light exposure is therapeutic but it is also toxic and the goal is finding balance. A family friend with type one diabetes counseled me decades ago after she had observed my situation when I was in my 20’s. What is helpful one day May not be the next. Keeping a brief journal then..that is the benefit. Taking stock of things. Having your own reference points.

    Personalizing your health situation based on whatever things you can discern about yourself ..that can bring you to a calmer place. Physicians will treat often in a reactive fashion. Let’s test. Let’s try this medication. But the more personal dimension is often more relevant. And the more you see patterns and personal tendencies the more you may figure out a path forward.

    When I had breast cancer years ago it was the surgeon who tried to have my light disorder evaluated through primary care. She had seen me for a year before my diagnosis and was quite taken with my apt description of the physiological fallout I anticipated in late winter and spring. Because it was not noticed in primary care I had ceased to discuss it. Neither of us succeeded in getting a diagnosis for that. But it was a turning point as I had considered I had primarily a mood disorder and I liked talk therapy to discuss things. Even though I never came to clarity through primary care..the surgeon’s powers of observation promoted in me a determination to understand the chronic storms of symptoms. And ultimately I benefited and this laid the foundation for self management.

    Best wishes! Hang in there!!
    🌱🧩🌺🛣️☀️🗾

    • 2
      @nunofyurs2956

      Did your primary doctor ever refer you to a neurologist? My primary couldn’t figure it out, so I took things into my own hands and saw any doctor that had a “ist” behind their speciality. With no results for my pain issues. I finally found a neurologist who sent me for a MRI on my brain and found leision’s, but did not give a diagnosis. He just said that’s normal for people in my age group. When I asked him if I needed to make a followup appointment, he said no. I wasn’t satisfied with that answer and therefore found another neurologist who looked at the previous results and examined me and told me that she wasn’t the neurologist that I needed to see, BUT she was going to order a series of test and make an appointment for me with the doctor that I DID need to see. That’s how I was finally diagnosed with MS after 3 years of excruciating pain and I don’t know how many visits to emergency rooms. Autoimmune diseases can be tricky.

    • 3
      @mercywilliams2698

      @nunofyurs2956Right! A maze to find any answers. My cancer surgeon and my psychiatrist tried for some time to find me primary care every primary thought my description for seasonal disorder were mood based. I accepted that except main problem was always muscle weakness and unrelenting fatigue fallout from everyday exertion not mood issues. I am ultra sensitive to sunlight. I wasn’t familiar with autoimmune and my guess is I was caught in the middle between specialists who thought I had underlying problem but unwilling to suggest possibilities. I also was sent back to primary care by ENT and GI doctors a chiropractor and several neurologists. I guess everyone passed the buck! When the chiropractor found evidence of a devastating head and spine injury in 2006..at least I began to progress forward realizing the fatigue and learning deficits and a seizure disorder had likely come from that. That was a huge help for me. Fell down a steep staircase as a two year old and my mother didn’t disclose it to others.

      Age 69 I now will no longer go to healthcare settings. Obviously an emergency now and then I have done that. But eventually I was so saturated with the negativity I said no more. I do self manage at this point and I at least have a peaceable time with reality this is now a more aggressive dynamic. I had lingering Covid too. I think the autoimmune condition is probably a hybrid. And one neurologist thought I had Parkinsons with something else. The last time I saw neurologist he could not order tests. I didn’t meet prior authorization for him. He was apologetic. So yes a long story! Thank you so much for your thoughts. Best wishes to you. 🌱🌸🌺🦋✨

  2. 10
    @brilynn25

    I’m sorry but sounds to me that she just gave up wants to feel bad for herself. I know plenty of people with ms and they don’t complain like this lady does.

    • 12
      @michaeloesterle6652

      Tell me you don’t understand the disease without telling me you don’t understood the disease. I have secondary progressive ms and it took me from being a gym rat to now needing a walker to walk. At 51.

    • 13
      @BigAL-Bama

      It affects everyone differently. Some have a worse prognosis than others. But continue to show us how little you know

    • 14
      @BigAL-Bama

      ​@michaeloesterle6652 There are so many conspiracy theorists peddling lies on these videos who have no idea what they are talking about. It’s staggering

    • 15
      @nunofyurs2956

      When she says throwing up triggered whatever this is lets you know that she hadn’t been diagnosed yet. I’ve been there, not knowing for three years why I was having this pain and not knowing what was causing it. Going to the emergency rooms and being in so much pain that people that were ahead of me were asking the nurses to help me next.

  3. 17
    @damienkinder9759

    There’s different levels to ms. I have been living with ms for 5 years and the disease has not taken away my ability to walk. However it has affected my speech, whereas I needed a speech therapist to show me how to get my speech back to a “ new norm “. Before I was diagnosed and receiving infusions ( medication ), my symptoms were numbness that started from my toes and moved throughout my body. The pain would last at most for a 1min and 30 sec and at the least 30sec. During my ms spells, I couldn’t move until the pain subsided. I literally could not move 🤷🏾‍♂️But thanx to the infusions, that block ms from attacking my body, I have not experience any ms spells that caused my body to lock up .🙏🏾
    Oh and for those that think she’s complaining too much…you wouldn’t understand what she’s going through, cause you’re not living with ms. The white splotches that you may have heard of that is seen on a photograph from a mri, are lesions that are found on the brain, spine etc. Lesions are wombs. So imagine having that and going through the pain and discomfort that they may cause. Not to mention those ms patience that go blind. Ms is where the immune system attacks the the protective covering of nerves, causing communication problems between the brain and the body.

    • 18
      @BigAL-Bama

      It affects everyone differently. My walking is affected (feet/legs numb, clumsy and stiff). I have intermittent swallowing/breathing issues ect. The brain lesions can’t actually be felt because the brain can’t feel pain, the pain comes from misfiring nerve signals. The spinal lesions can cause a lot of pain too(I have a lot of spinal cord damage). The medications are for preventing new damage but don’t repair the damage already done unfortunately (I’m on Kesimpta). I’ve also had it for at least 5 years judging by the symptoms/damage done but I didn’t get diagnosed until last year after letting it run rampant for too long. If I had gotten treatment sooner, I wouldn’t be dealing with as much damage as I have now.

  4. 19
    @Queenmom313

    I love you Christina! I have had some weird symptoms, for years, myself, and I am just now being sent to a Neurologist (I asked for the referral, myself.) I am ready for answers, too. I have read your book (fabulous) and I having been watching various videos of yours…you are such an inspiration to all of us. Keep On, girl!

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